What is clear is that when humanity needed a way to deliver mRNA to human cells to arrest the pandemic, there was only one reliable method available-and it wasn’t one originated in-house by Pfizer, Moderna, BioNTech or any of the other major vaccine companies.Ī months-long investigation by Forbes reveals that the scientist most responsible for this critical delivery method is a little-known 57-year-old Canadian biochemist named Ian MacLachlan. It’s a complicated saga involving 15 years of legal battles and accusations of betrayal and deceit. Yet the story of how Moderna, BioNTech and Pfizer managed to create that vital delivery system has never been told. “It is how to make sure the mRNA molecule will go into your cells and give the instructions.” “The whole mRNA platform is not how to build an mRNA molecule that’s the easy thing,” Bourla says. ![]() The Austrian manufacturing plant was one of the few places on earth that made the required lipid nanoparticles, and Bourla insisted Şahin go with him personally to press their case. But to get it safely into human cells, the mRNA needed to be wrapped in microscopic fragments of fat known as lipids. The Pfizer-BioNTech vaccine had been engineered with messenger RNA technology that instructs the body’s immune system to combat the coronavirus.
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